Product Description

Species: Mouse
Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 50 pg/ml
Detection Range: 250-16,000 pg/ml
Assay Length: 3.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Long Name: Glucagon-like peptide-1
Synonyms: GLP1; GLP-1; glucagon-like peptide 1;
Background: Glucagon-like peptide-1 (GLP-1) is a 30 or 31 amino acid long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon peptide. It is produced and secreted by intestinal enteroendocrine L-cells and certain neurons within the nucleus of the solitary tract in the brainstem upon food consumption. The initial product GLP-1 (1–37) is susceptible to amidation and proteolytic cleavage which gives rise to the two truncated and equipotent biologically active forms, GLP-1 (7–36) amide and GLP-1 (7–37). Active GLP-1 composes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region.
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REFERENCE LIBRARY

No:SEKM-0148
Size: