Porcine IL-17A Elisa Kit


Product Description

Species: Porcine
Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 20 pg/ml
Detection Range: 78.1-5,000 pg/ml
Assay Length: 2-2.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Long Name: Interleukin 17
Synonyms: CTLA-8; IL17; IL-17; IL17A; IL-17A
Background: The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.
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REFERENCE LIBRARY

No:SEKP-0173
Size: