Bovine IL-33 Elisa Kit

No :   SEKB-0187
Size :   
Quantity :   
PRODUCT DESCRIPTION

Species :

Bovine

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

5 pg/ml

Detection Range :

25-1600 pg/ml

Assay Length :

2-2.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Interleukin 33

Synonyms :

IL33; C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV; Interleukin 33; IL-33

Background :

IL-33 (Interleukin-33) is released from physically damaged or necrotic cells. It triggers Th2-biased immune cell activation at sites of inflammation as well as regulatory T cell and M2 macrophage expansion. It additionally induces angiogenesis, promotes tumor cell migration and invasion, limits cardiac myocyte hypertrophy, and limits the development of atherosclerotic plaques. IL-33 signals through a receptor complex composed of ST2 and IL-1 RAcP. IL-1 RAcP also associates with IL-1 RI, IL-1 RII, IL-1 R6, and SCF R/c-kit. Soluble isoforms of ST2 and IL-1 RAcP function as decoy receptors that regulate IL-33 bioactivity.
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