Feline IL-31 Elisa Kit

Species :

Feline

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

11 pg/ml

Detection Range :

62-4000 pg/ml

Assay Length :

2-2.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Interleukin 31

Synonyms :

IL31; IL-31; IL-31; Interleukin-31; Interleukin 31

Background :

Interleukin 31 (IL-31) is a secreted, T-cell-derived, 24-kDa, short-chain member of the alpha-helical family of cytokines. The mature region is 141 amino acids (aa) in length and exhibits four alpha-helices. Human and mouse IL-31 are highly divergent at 24% aa sequence identity. The receptor for IL-31 is found on keratinocytes and monocytes. It is a heterodimer composed of the Oncostatin M receptor and a novel gp130-related molecule. IL-31 may be involved in pruritis, or skin itching.