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My CartStorage：Store at -20℃，2 years.Avoid freeze/thaw cycles.
Appearance：Lyophilized powder
Gene ID：80024
Application：Blocking Peptide of K109657P Antibody
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| Name | SLC8B1 Antibody Blocking Peptide |
| Appearance | Lyophilized powder |
| Storage | Store at -20℃，2 years.Avoid freeze/thaw cycles. |
| Swiss Prot | Q6J4K2 |
| Gene ID | 80024 |
| Background | Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion， by mediating the exchange of 3 sodium ions per 1 calcium ion (PubMed:20018762， PubMed:22829870， PubMed:23056385， PubMed:24898248， PubMed:28219928). Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival， notably in cardiomyocytes (By similarity). Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion， thereby affecting cytoplasmic calcium responses (PubMed:23056385). Required for store-operated Ca2+?entry (SOCE) and Ca2+?release-activated Ca2+?(CRAC) channel regulation: sodium transport by SLC8B1 leads to promote calcium-shuttling that modulates mitochondrial redox status， thereby regulating SOCE activity (PubMed:28219928). Involved in B-lymphocyte chemotaxis (By similarity). Able to transport Ca2+?in exchange of either Li+?or Na+， explaining how Li+?catalyzes Ca2+?exchange (PubMed:15060069). In contrast to other members of the family its function is independent of K+?(PubMed:15060069). |
| Application | Blocking Peptide of K109657P Antibody |
| Source | Synthetic |
| Purification Method | HPLC |
| Biological Activity | Not tested |
| Unit | Piece |
| Specification | 500ug |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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