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My CartReactivity：Human,Rat,Mouse
Application：IHC,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：54956
Purity：PARP16
Qty：
Size：
| Name | Anti-PARP16 Polyclonal Antibody |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:3000-5000.IHC 1:25-100. |
| Target | Rabbit |
| Background | Intracellular mono-ADP-ribosyltransferase that plays a role in different processes， such as protein translation and unfolded protein response (UPR)， through the mono-ADP-ribosylation of proteins involved in those processes (PubMed:22701565， PubMed:23103912， PubMed:25043379， PubMed:34314702).Acts as an inhibitor of protein translation by catalyzing mono-ADP-ribosylation of ribosomal subunits， such as RPL14 and RPS6， thereby inhibiting polysome assembly and mRNA loading (PubMed:34314702).Mono-ADP-ribosylation of ribosomal subunits is promoted by NMNAT2 (PubMed:34314702).Involved in the unfolded protein response (UPR) by ADP-ribosylating and activating EIF2AK3 and ERN1， two important UPR effectors (PubMed:23103912).May also mediate mono-ADP-ribosylation of karyopherin KPNB1 a nuclear import factor (PubMed:22701565).May not modify proteins on arginine or cysteine residues compared to other mono-ADP-ribosyltransferases (PubMed:22701565). |
| Swiss Prot | Q8N5Y8 |
| Gene ID | 54956 |
| Subcellular Location | Cell membrane Cytoplasm Nucleus |
| Immunogen | Recombinant protein of human PARP16 |
| Public Immunogen Range | 1-280aa |
| Calculated MW | 23/36KDa |
| Observed MW | Fruit fly |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Purity | PARP16 |
| Conjugation Concentration | bottle |
| Conjugation | 34KDa |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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