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My CartReactivity：Human,Rat,Mouse
Application：IF,WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：1374
Host：Rabbit
Qty：
Size：
| Name | Anti-CPT1A Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:1000-5000. IHC 1:50-200. IF 1:50-200. |
| Target | CPT1A |
| Background | The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Swiss Prot | P50416 |
| Gene ID | 1374 |
| Subcellular Location | Cytoplasm Cell membrane |
| Immunogen | Recombinant protein of human CPT1A |
| Public Immunogen Range | 520-720aa |
| Calculated MW | 88kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human Rat Mouse |
| Application | IF WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with CPT1A antibody diluted at 1:1000;Lane: MCF7.
Immunohistochemistry of paraffin-embedded Human colon with CPT1A antibody diluted at 1:100.
Immunofluorescence analysis of HepG2 cells using CPT1A antibody diluted at 1:100.
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PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells
Click to check >>Author：You J H
IF：11.1610
Publish_to：Journal of Experimental & Clinical Cancer Research
PMID：34749765
Whey protein hydrolysate alleviated atherosclerosis and hepatic steatosis by regulating lipid metabolism in apoE-/- mice fed a Western diet
Click to check >>Author：王凯
IF：6.4750
Publish_to：Food Research International
PMID：
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