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My CartReactivity：Human,Mouse,Rat
Application：WB,IF
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：3661
Host：Rabbit
Qty：
Size：
| Name | Anti-IRF3 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-2000.IF 1:50-200 |
| Target | IRF3 |
| Background | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Swiss Prot | Q14653 |
| Gene ID | 3661 |
| Subcellular Location | Cytoplasm Nucleus |
| Immunogen | Recombinant protein of human IRF3 |
| Public Immunogen Range | 1-260aa |
| Calculated MW | 12/16/33/47/49kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide，50% glycerol，pH7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | IF WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Western blot analysis with IRF3 antibody diluted at 1:1000;Lane: THP-1 HT-29.
Immunofluorescence analysis of THP-1 cells using IRF3 antibody diluted at 1:100.
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Multifunctional hybrid exosomes enhanced cancer chemo-immunotherapy by activating the STING pathway
Click to check >>Author：Lili Cheng, Peng Zhang, Yadong Liu, Zhuoyin Liu, Junjie Tang, Langtao Xu, Jie Liu
IF：14.0000
Publish_to：BIOMATERIALS
PMID：37531777
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