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My CartReactivity：Human,Rat,Mouse
Application：IHC,IF
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze/thaw cycles.
Gene ID：3553
Host：Rabbit
Qty：
Size：
| Name | Anti-IL1B Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | IHC 1:50-200. IF 1:50-200. |
| Target | IL1B |
| Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
| Swiss Prot | P01584 |
| Gene ID | 3553 |
| Subcellular Location | Cytoplasm |
| Immunogen | A synthetic peptide of human IL1B |
| Public Immunogen Range | 195-245/269aa |
| Calculated MW | 30kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze/thaw cycles. |
| Unit | Piece |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Rat Mouse |
| Application | IHC IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded Human lung cancer with IL1B antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human stomach cancer with IL1B antibody diluted at 1:100.
Immunofluorescence analysis of A431 cells using IL1B antibody diluted at 1:100.
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Exogenous carbon monoxide protects against mitochondrial DNA induced hippocampal pyroptosis in a model of hemorrhagic shock and resuscitation
Click to check >>Author：Fu L
IF：4.1010
Publish_to：International Journal of Molecular Medicine
PMID：32124959
Hydrogen gas post conditioning attenuates early neuronal pyroptosis in a rat model of subarachnoid hemorrhage through the mitoK ATP signaling pathway
Click to check >>Author：Zhang C S
IF：2.4470
Publish_to：Experimental and Therapeutic Medicine
PMID：34149882
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