English Name |
Anti-TNF Polyclonal Antibody |
Chinese Name |
肿瘤坏死因子抗体 |
Target |
TNF |
Synonym |
Tumor necrosis factor-α, TNFalpha, APC1, Cachectin, DIF, Differentiation inducing factor, Macrophage cytotoxic factor, MCF, Necrosin, TNF a, TNF-alpha, TNF, TNF Macrophage Derived, TNF Monocyte Derived, TNF Superfamily Member 2, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor Precurso, Tumour Necrosis Factor Alpha |
Backgroud |
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
Swiss Prot |
P01375 |
Gene ID |
7124 |
Subcellular Localization |
Cell membrane Membrane Secreted Single-pass type II membrane protein Single-pass type II membrane protein |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Protein MW |
26kDa |
Dilution Ratio |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
Immunogen |
A synthetic peptide of human TNF |
Public Immunogen Range |
1-100aa |
Purification Method |
Affinity purification |
Storage Buffer |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
Storage |
Store at -20℃, avoid freeze/thaw cycles. |
Unit |
Piece |
Cross-Reactivity |
Human Rat Mouse |
Application |
WB IHC IF |
Specification |
50ul 100ul |