Gene Name |
JNK2/MAPK9 |
Synonyms |
c Jun N terminal kinase 2,JNK 55,JNK2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,MAP kinase 9,MAPK 9,MAPK9,p54a,p54aSAPK,PRKM9,SAPK |
English Name |
Recombinant human JNK2/MAPK9 protein |
Full Name |
mitogen-activated protein kinase 9 |
Chinese Name |
丝裂原活化蛋白激酶9 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
P45984 |
Gene ID |
5601 |
Reactivity |
Human Mouse Rat (Chicken) |
Molecular Weight |
42kDa |
Interval Range |
55-424aa |
Background |
The protein encoded by this gene is a member of the MAP kinase family.MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli.It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway.This gene and MAPK8 are also known as c-Jun N-terminal kinases.This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells.Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation.Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |