Gene Name |
AGT |
Synonyms |
AGT,Ang I Angiotensin 2,Ang II Angiotensin 3,Ang III,Angiotensin I,Angiotensin II,Angiotensin III,Angiotensinogen,ANHU,Des Asp[1] angiotensin II,FLJ92595,FLJ97926,Serpin A8,SERPINA8 |
English Name |
Recombinant human AGT protein |
Full Name |
angiotensinogen |
Chinese Name |
血管紧张素原 |
Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
Purity |
≥85% by SDS-PAGE. |
Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks, stored at < -20℃ for 1 year. |
Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
Concentration |
1mg/ml by SDS-PAGE. |
Swiss Prot |
P01019 |
Gene ID |
183 |
Reactivity |
Human Mouse Rat (Cat Sheep Horse Gorilla) |
Molecular Weight |
48kDa |
Interval Range |
44-485aa |
Background |
he protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure.The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II.The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development.Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. |
Application |
Immunology research |
Source |
E.coli |
Purification Method |
NI-NTA affinity purification |
Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
Endotoxin |
Not measured |
Biological Activity |
N0 |
Lable Information |
With a 6×His tag at the N/C-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |