| Gene Name |
RPSA |
| Synonyms |
37/67 kDa laminin receptor，37LRP，40S ribosomal protein SA，67 kDa laminin receptor，67LR，LAMBR，Laminin receptor，Laminin receptor 1，LamR，LAMR1，LBP/p40，LRP，LRP/LR，NEM/1CHD4，p40，ribosomal protein SA，RPSA |
| English Name |
Recombinant human RPSA protein |
| Full Name |
ribosomal protein SA |
| Chinese Name |
核糖体蛋白SA |
| Appearance |
Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. |
| Purity |
≥85% by SDS-PAGE. |
| Storage |
Reconstituted protein solution can be stored at 4-7℃ for 1-2 weeks， stored at < -20℃ for 1 year. |
| Transport Condition |
The product is shipped at -20℃ temperature. Upon receipt, store it immediately at the temperature listed below. |
| Concentration |
1mg/ml by SDS-PAGE. |
| Swiss Prot |
P08865 |
| Gene ID |
3921 |
| Reactivity |
Human Mouse Rat (Bovine Zebrafish Pig Sheep) |
| Molecular Weight |
33kDa |
| Interval Range |
1-295aa |
| Background |
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes.They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis.Many of the effects of laminin are mediated through interactions with cell surface receptors.These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins.This gene encodes a high-affinity, non-integrin family, laminin receptor 1.This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein.The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function.It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts.Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events.Two alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Application |
Immunology research |
| Source |
E.coli |
| Purification Method |
NI-NTA affinity purification |
| Solvent |
Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| Endotoxin |
Not measured |
| Biological Activity |
N0 |
| Lable Information |
With a 6×His tag at the N/C-terminus. |
| Unit |
Piece |
| Specification |
10ug 50ug 100ug 1mg |
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