English Name |
Anti-VEGFR1 Polyclonal Antibody |
Chinese Name |
血管内皮生长因子受体1抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
WB 1:500-2000.IHC 1:50-100 |
Target |
VEGFR1 |
Synonyms |
VEGF-R1, VEGFR-1, VEGF Receptor 1, FLT-1, vascular permeability factor receptor, vascular endothelial growth factor receptor, vascular endothelial growth factor receptor-1, fms-related tyrosine kinase 1, vascular endothelial growth factor/vascular permeability factor receptor, AI323757, FLT, FLT1, sFlt1, VGFR1_HUMAN, VGFR1_MOUSE |
Background |
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
Swiss Prot |
P17948 |
Gene ID |
2321 |
Subcellular Location |
Cell membrane,Cytoplasm,Endosome,Secreted,Single-pass type I membrane protein |
Immunogen |
Recombinant protein of human VEGFR1 |
Public Immunogen Range |
20-300aa |
Calculated MW |
39/41/52-82/150kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Unit |
Piece |
Specification |
50ul 100ul |