Anti-CD48(FITC) Monoclonal Antibody
Cat.No:K010811M-SAlexa Fluor 750 Solarbio
Reactivity:Human
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
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Anti-CD48(FITC) Monoclonal AntibodySAlexa Fluor 750Reactivity:Human
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
Qty:
Size:
Reactivity | Human |
Background | Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation (PubMed:27249817,PubMed:12007789).Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex (PubMed:19494291).In turn,promotes LCK phosphorylation and subsequent activation (PubMed:12007789).Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells (PubMed:9841922,PubMed:27249817). |
Subtype | IgG1,κ |
Storage | Store at 4℃ in dark.Do not freeze. |
Host | Mouse |
Application | FCM |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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