Anti-CD49d(FITC) Monoclonal Antibody
Cat.No:K010813M-Cy3 Solarbio
Reactivity:Human
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
Qty:
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My CartReactivity:Human
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
Qty:
Size:
Reactivity | Human |
Background | Integrin alpha 4 (also called CD49d) is a 150 kDa protein that possesses a large extracellular domain involved in ligand binding,a single transmembrane domain,and an intracellular regulatory domain possessing multiple sites for phosphorylation. Integrin alpha 4 forms heterodimers with integrins beta 1 and beta 7. Integrin alpha 4 is expressed on leukocytes and leukocyte precursors,neural crest cells,and developing skeletal muscles and is essential for embryogenesis,hematopoiesis,and immune responses. The presence of integrin alpha 4 promotes cell migration and inhibits cell spreading and contractility. Integrin alpha 4 function has been implicated in the pathogenesis of multiple diseases including asthma,rheumatoid arthritis,Crohn's disease,ulcerative colitis,hepatitis C,and multiple sclerosis,and therefore,modulation of integrin alpha 4 function has become an important target for drug discovery. |
Subtype | IgG1,κ |
Storage | Store at 4℃ in dark.Do not freeze. |
Host | Mouse |
Application | FCM |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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