Anti-CD49f(FITC) Monoclonal Antibody
Cat.No:K010814M-Cy7 Solarbio
Reactivity:Human
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
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My CartReactivity:Human
Storage:Store at 4℃ in dark.Do not freeze.
Host:Mouse
Qty:
Size:
Reactivity | Human |
Background | Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface,but,unlike most other cell surface receptors,they bind ligands with very low affinity. Due to their weak individual binding,integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Integrin alpha 6 complexes are receptors for laminins,which are components of basement membranes. Integrin alpha 6 complexes may play an important role in embryogenesis. |
Subtype | IgG2b,κ |
Storage | Store at 4℃ in dark.Do not freeze. |
Host | Mouse |
Application | FCM |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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