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My Cart> Antibodies > Primary Antibodies > Anti-CD8a(AF488) Monoclonal AntibodySAlexa Fluor 568Reactivity：Mouse
Application：SAlexa Fluor 568
Clone Type：Monoclonal Antibody
Storage：Store at 2-8℃ in dark.Do not freeze.
Gene ID：12525
Purity：CD8a(AF488)
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| Reactivity | Mouse |
| Background | CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains.It can be present as a homodimer of CD8 or as a heterodimer of CD8 and CD8 (PMID: 3264320;8253791).CD8 is found on most thymocytes.The majority of class I-restricted T cells express mostly the CD8 heterodimer while CD8 homodimers alone have been found on some gut intraepithelial T cells on some T cell receptor (TCR) T cells and on NK cells (PMID: 2111591;1831127;8420975).CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079).During T cell development CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084). |
| Subtype | IgG2a κ |
| Storage | Store at 2-8℃ in dark.Do not freeze. |
| Application | IF |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
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