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My CartReactivity：Mouse,Human,Rat
Application：HRP
Clone Type：Monoclonal Antibody
Storage：Store at -20℃.Avoid freeze/thaw cycles.
Gene ID：9451
Purity：PERK/EIF2AK3
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| Reactivity | Mouse,Human,Rat |
| Background | PERK also named as EIF2AK3 or PEK belongs to the protein kinase superfamily Ser/Thr protein kinase family and GCN2 subfamily.It acts as a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to various stress conditions.PERK and EIF2AK4 also have a functional role on regulating translation under non-stressed conditions apart from their long established roles as stress kinases (PMID: 21638082).Defects in EIF2AK3 are the cause of Wolcott-Rallison syndrome (WRS).The molecular mass of PERK is 125 kDa and can be detected as 140 kDa or 170kDa due to some modifications such as glycosylation and phosphorylation (PMID: 20851775 24371088 21703327). |
| Subtype | IgG1 |
| Storage | Store at -20℃.Avoid freeze/thaw cycles. |
| Application | WB ELISA |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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