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My CartReactivity：Human,Rat
Application：Cy3
Clone Type：Monoclonal Antibody
Storage：Store at -20℃.Avoid freeze/thaw cycles.
Gene ID：59341
Purity：TRPV4
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| Reactivity | Human,Rat |
| Background | Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity (PubMed:16293632， PubMed:18695040， PubMed:18826956， PubMed:22526352， PubMed:23136043， PubMed:29899501). Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification (PubMed:18695040， PubMed:18826956， PubMed:29899501). Also activated by heat， low pH， citrate and phorbol esters (PubMed:16293632， PubMed:18695040， PubMed:18826956， PubMed:20037586， PubMed:21964574， PubMed:25256292). Increase of intracellular Ca2+ potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism (PubMed:12724311， PubMed:18826956). Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers (By similarity). |
| Subtype | IgG |
| Storage | Store at -20℃.Avoid freeze/thaw cycles. |
| Application | WB ELISA |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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