Anti-CHP2 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CHP2

Immunogen :

A synthetic peptide of CHP2

Synonym :

HCA520

Isotype :

IgG

Gene ID :

63928

Clone No :

Swiss Port :

O43745

Molecular weight :

22kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+?exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.