Anti-MRPL22 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

MRPL22

Immunogen :

A synthetic peptide of MRPL22

Synonym :

HSPC158; L22mt; MRP-L22; MRP-L25; RPML25; mitochondrial ribosomal protein L22

Isotype :

IgG

Gene ID :

29093

Clone No :

Swiss Port :

Q9NWU5

Molecular weight :

14/23kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Predicted:Cow

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cytoplasm Cell membrane

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.