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Anti-PTK2B Polyclonal Antibody

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Cat.No：K111002P-SAlexa Fluor 405 Solarbio

Reactivity：Human,Rat,Mouse

Storage：Store at -20℃. Avoid freeze/thaw cycles.

Host：Rabbit

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Product Information

Reactivity	Human,Rat,Mouse
Background	This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene
Subtype	IgG
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Host	Rabbit
Application	IHC

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.