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Anti-ATXN1 Polyclonal Antibody

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Cat.No：K111095P-SAlexa Fluor 350 Solarbio

Reactivity：Human,Rat,Mouse

Storage：Store at -20℃. Avoid freeze/thaw cycles.

Host：Rabbit

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Product Information

Reactivity	Human,Rat,Mouse
Background	The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to ch
Subtype	IgG
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Host	Rabbit
Application	IHC

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

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